FMOD Antibody
Product Specifications
Background
Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix.
NCBI Gene ID
2331
Swiss Prot
Q06828
Accession Number
Q06828
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This FMOD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-364 amino acids from the C-terminal region of human FMOD.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
43 kDa
Fragment
Rabbit Ig
Symbol
FMOD
NCBI Official Name
Fibromodulin
NCBI Organism
Homo sapiens
Background Reference 01
Ehret, G.B., et.al, Eur. J. Hum. Genet. 17 (12), 1650-1657 (2009)
Background Reference 02
Tillgren, V., et.al, J. Biol. Chem. 284 (42), 28543-28553 (2009)
Other Product Names
Fibromodulin, FM, Collagen-binding 59 kDa protein, Keratan sulfate proteoglycan fibromodulin, KSPG fibromodulin, FMOD, FM, SLRR2E
Tested Applications
WB, IHC-P, Flow
Protein ID
223590208
Physical Properties
Liquid
Curated Selection
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