ALOX15B Antibody

Product Specifications

Background

ALOX15B encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17.

NCBI Gene ID

247

Swiss Prot

O15296

Accession Number

O15296

Host

Rabbit

Reactivity

Human

Immunogen

This ALOX15B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 597-627 amino acids from the C-terminal region of human ALOX15B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

76 kDa

Fragment

Rabbit Ig

Symbol

ALOX15B

NCBI Official Name

Arachidonate 15-lipoxygenase B

NCBI Organism

Homo sapiens

Background Reference 01

Wecksler, A.T., et.al., Biochemistry 48 (36), 8721-8730 (2009)

Background Reference 02

Kawakami, Y., et.al, Biosci. Biotechnol. Biochem. 73 (8), 1811-1817 (2009)

Other Product Names

Arachidonate 15-lipoxygenase B, 15-LOX-B, 15-lipoxygenase 2, 15-LOX-2, Arachidonate 15-lipoxygenase type II, Linoleate 13-lipoxygenase 15-LOb, 11311-, ALOX15B