DEK Antibody
Product Specifications
Background
DEK is a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases.
NCBI Gene ID
7913
Swiss Prot
P35659
Accession Number
P35659
Host
Rabbit
Reactivity
Human
Immunogen
This DEK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-364 amino acids from the C-terminal region of human DEK.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
43 kDa
Fragment
Rabbit Ig
Symbol
DEK
NCBI Official Name
Protein DEK
NCBI Organism
Homo sapiens
Background Reference 01
Sawatsubashi, S., et.al., Genes Dev. 24 (2), 159-170 (2010)
Background Reference 02
Khodadoust, M.S., et.al., Cancer Res. 69 (16), 6405-6413 (2009)
Other Product Names
Protein DEK, DEK
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
544150
Physical Properties
Liquid
Curated Selection
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