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CDC73 Antibody

Product Specifications

Background

CDC73 encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin.

NCBI Gene ID

79577

Swiss Prot

Q6P1J9

Accession Number

Q6P1J9

Host

Rabbit

Reactivity

Human

Immunogen

This CDC73 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-161 amino acids from the Central region of human CDC73.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=63-825

Calculated Molecular Weight

61 kDa

Fragment

Rabbit Ig

Symbol

CDC73

NCBI Official Name

Parafibromin

NCBI Organism

Homo sapiens

Background Reference 01

Vierimaa, O., et.al., J. Endocrinol. Invest. 32 (6), 512-518 (2009)

Background Reference 02

Hahn, M.A., et.al., J. Endocrinol. 201 (3), 387-396 (2009)

Other Product Names

Parafibromin, Cell division cycle protein 73 homolog, Hyperparathyroidism 2 protein, CDC73, C1orf28, HRPT2

Tested Applications

WB, IHC-P, IF, Flow

Protein ID

74749063

Physical Properties

Liquid

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