CDC73 Antibody
Product Specifications
Background
CDC73 encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin.
NCBI Gene ID
79577
Swiss Prot
Q6P1J9
Accession Number
Q6P1J9
Host
Rabbit
Reactivity
Human
Immunogen
This CDC73 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-161 amino acids from the Central region of human CDC73.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
61 kDa
Fragment
Rabbit Ig
Symbol
CDC73
NCBI Official Name
Parafibromin
NCBI Organism
Homo sapiens
Background Reference 01
Vierimaa, O., et.al., J. Endocrinol. Invest. 32 (6), 512-518 (2009)
Background Reference 02
Hahn, M.A., et.al., J. Endocrinol. 201 (3), 387-396 (2009)
Other Product Names
Parafibromin, Cell division cycle protein 73 homolog, Hyperparathyroidism 2 protein, CDC73, C1orf28, HRPT2
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
74749063
Physical Properties
Liquid
Frequently Asked Questions
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