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TPH2 Antibody

Product Specifications

Background

This protein is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control.

NCBI Gene ID

121278

Swiss Prot

Q8IWU9

Accession Number

Q8IWU9

Host

Rabbit

Reactivity

Human

Immunogen

This TPH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-193 amino acids from the Central region of human TPH2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

56 kDa

Fragment

Rabbit Ig

Symbol

TPH2

NCBI Official Name

Tryptophan 5-hydroxylase 2

NCBI Organism

Homo sapiens

Background Reference 01

Khatua, A.K., et.al., Virology 400 (1), 68-75 (2010)

Background Reference 02

Koning, F.A., et.al., J. Virol. 83 (18), 9474-9485 (2009)

Other Product Names

Tryptophan 5-hydroxylase 2, Neuronal tryptophan hydroxylase, Tryptophan 5-monooxygenase 2, TPH2, NTPH

Tested Applications

WB, IHC-P, Flow

Protein ID

30580625

Physical Properties

Liquid

Frequently Asked Questions

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