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PEX14 Antibody

Product Specifications

Background

PEX14 belongs to the peroxin 14 family. It is a component of the peroxisomal translocation machinery with PEX13 and PEX17 and interacts with both the PTS1 and PTS2 receptors. PEX14 binds directly to PEX17. Defects in PEX14 are the cause of peroxisome biogenesis disorder complementation group K (PBD-CGK) [MIM:601791] and Zellweger syndrome (ZWS) [MIM:214100].

NCBI Gene ID

5195

Swiss Prot

O75381

Accession Number

O75381

Host

Rabbit

Reactivity

Human

Immunogen

This PEX14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 343-370 amino acids from the C-terminal region of human PEX14.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

41 kDa

Fragment

Rabbit Ig

Symbol

PEX14

NCBI Official Name

Peroxisomal membrane protein PEX14

NCBI Organism

Homo sapiens

Background Reference 01

Neufeld C., et.al., EMBO J. 28:745-754 (2009) .

Other Product Names

Peroxisomal membrane protein PEX14, PTS1 receptor-docking protein, Peroxin-14, Peroxisomal membrane anchor protein PEX14, PEX14

Tested Applications

WB, IHC-P, Flow

Physical Properties

Liquid

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