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CDC20 Antibody

Product Specifications

Background

CDC20 is an activating regulatory factor for the APC/C (anaphase promoting complex/cyclosome) . It activates the ubiquitination activity of the APC/C. CDC20 confers a strict destruction-box (D-box) dependence on APC. Levels of CDC20, as well as its binding to APC, peak in mitosis and decrease drastically at early G1.

NCBI Gene ID

991

Swiss Prot

Q12834

Accession Number

Q12834

Host

Rabbit

Reactivity

Human

Immunogen

This CDC20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-84 amino acids from the N-terminal region of human CDC20.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Pig

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

55 kDa

Fragment

Rabbit Ig

Symbol

CDC20

NCBI Official Name

Cell division cycle protein 20 homolog

NCBI Organism

Homo sapiens

Background Reference 01

Ge S., et.al., Cell Cycle 8:167-171 (2009) .

Background Reference 02

Gauci S., et.al., Anal. Chem. 81:4493-4501 (2009) .

Other Product Names

Cell division cycle protein 20 homolog, p55CDC, CDC20

Tested Applications

WB, Flow

Protein ID

37537762

Physical Properties

Liquid

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