CDC20 Antibody
Product Specifications
Background
CDC20 is an activating regulatory factor for the APC/C (anaphase promoting complex/cyclosome) . It activates the ubiquitination activity of the APC/C. CDC20 confers a strict destruction-box (D-box) dependence on APC. Levels of CDC20, as well as its binding to APC, peak in mitosis and decrease drastically at early G1.
NCBI Gene ID
991
Swiss Prot
Q12834
Accession Number
Q12834
Host
Rabbit
Reactivity
Human
Immunogen
This CDC20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-84 amino acids from the N-terminal region of human CDC20.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Pig
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
55 kDa
Fragment
Rabbit Ig
Symbol
CDC20
NCBI Official Name
Cell division cycle protein 20 homolog
NCBI Organism
Homo sapiens
Background Reference 01
Ge S., et.al., Cell Cycle 8:167-171 (2009) .
Background Reference 02
Gauci S., et.al., Anal. Chem. 81:4493-4501 (2009) .
Other Product Names
Cell division cycle protein 20 homolog, p55CDC, CDC20
Tested Applications
WB, Flow
Protein ID
37537762
Physical Properties
Liquid
Curated Selection
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