LOX Antibody
Product Specifications
Background
LOX is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression.
NCBI Gene ID
4015
Swiss Prot
P28300
Accession Number
P28300
Host
Rabbit
Reactivity
Human
Immunogen
This LOX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-260 amino acids from the Central region of human LOX.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-793
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Symbol
LOX
NCBI Official Name
Protein-lysine 6-oxidase
NCBI Organism
Homo sapiens
Background Reference 01
Mariani, T.J., et.al., Matrix 12 (3), 242-248 (1992)
Other Product Names
Protein-lysine 6-oxidase, Lysyl oxidase, LOX
Tested Applications
WB, Flow
Physical Properties
Liquid
Curated Selection
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