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ADRBK2 Antibody

Product Specifications

Background

ADRBK2 is the beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.

NCBI Gene ID

157

Swiss Prot

P35626

Accession Number

P35626

Host

Rabbit

Reactivity

Human

Immunogen

This ADRBK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human ADRBK2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

80 kDa

Fragment

Rabbit Ig

Symbol

ADRBK2

NCBI Official Name

Beta-adrenergic receptor kinase 2

NCBI Organism

Homo sapiens

Background Reference 01

Gratacos, M., et.al., Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (6), 808-816 (2009)

Background Reference 02

Rao, J.S., et.al., Int. J. Neuropsychopharmacol. 12 (6), 851-860 (2009)

Other Product Names

Beta-adrenergic receptor kinase 2, Beta-ARK-2, G-protein-coupled receptor kinase 3, ADRBK2, BARK2, GRK3

Tested Applications

WB, IHC-P

Protein ID

116241253

Physical Properties

Liquid

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