ADRBK2 Antibody
Product Specifications
Background
ADRBK2 is the beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.
NCBI Gene ID
157
Swiss Prot
P35626
Accession Number
P35626
Host
Rabbit
Reactivity
Human
Immunogen
This ADRBK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human ADRBK2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
80 kDa
Fragment
Rabbit Ig
Symbol
ADRBK2
NCBI Official Name
Beta-adrenergic receptor kinase 2
NCBI Organism
Homo sapiens
Background Reference 01
Gratacos, M., et.al., Am. J. Med. Genet.Neuropsychiatr. Genet. 150B (6), 808-816 (2009)
Background Reference 02
Rao, J.S., et.al., Int. J. Neuropsychopharmacol. 12 (6), 851-860 (2009)
Other Product Names
Beta-adrenergic receptor kinase 2, Beta-ARK-2, G-protein-coupled receptor kinase 3, ADRBK2, BARK2, GRK3
Tested Applications
WB, IHC-P
Protein ID
116241253
Physical Properties
Liquid
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