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SPRR1B Antibody

Product Specifications

Background

SPRR1B is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.

NCBI Gene ID

6699

Swiss Prot

P22528

Accession Number

P22528

Host

Rabbit

Reactivity

Human

Immunogen

This SPRR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-89 amino acids from the C-terminal region of human SPRR1B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Other

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

10 kDa

Fragment

Rabbit Ig

Symbol

SPRR1B

NCBI Official Name

Cornifin-B

NCBI Organism

Homo sapiens

Background Reference 01

Stemmler, S., et.al., Int. J. Immunogenet. 36 (4), 217-222 (2009)

Background Reference 02

Kainu, K., et.al., Exp. Dermatol. 18 (2), 109-115 (2009)

Other Product Names

Cornifin-B, 149 kDa pancornulin, Small proline-rich protein IB, SPR-IB, SPRR1B

Tested Applications

WB, IHC-P

Protein ID

84028265

Physical Properties

Liquid

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