SPRR1B Antibody
Product Specifications
Background
SPRR1B is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. Can function as both amine donor and acceptor in transglutaminase-mediated cross-linkage.
NCBI Gene ID
6699
Swiss Prot
P22528
Accession Number
P22528
Host
Rabbit
Reactivity
Human
Immunogen
This SPRR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-89 amino acids from the C-terminal region of human SPRR1B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-762
Calculated Molecular Weight
10 kDa
Fragment
Rabbit Ig
Symbol
SPRR1B
NCBI Official Name
Cornifin-B
NCBI Organism
Homo sapiens
Background Reference 01
Stemmler, S., et.al., Int. J. Immunogenet. 36 (4), 217-222 (2009)
Background Reference 02
Kainu, K., et.al., Exp. Dermatol. 18 (2), 109-115 (2009)
Other Product Names
Cornifin-B, 149 kDa pancornulin, Small proline-rich protein IB, SPR-IB, SPRR1B
Tested Applications
WB, IHC-P
Protein ID
84028265
Physical Properties
Liquid
Curated Selection
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