SPG20 Antibody
Product Specifications
Background
SPG20 is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor.
NCBI Gene ID
23111
Swiss Prot
Q8N0X7
Accession Number
Q8N0X7
Host
Rabbit
Reactivity
Human
Immunogen
This SPG20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-45 amino acids from the N-terminal region of human SPG20.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
73 kDa
Fragment
Rabbit Ig
Symbol
SPG20
NCBI Official Name
Spartin
NCBI Organism
Homo sapiens
Background Reference 01
Milewska, M., et.al., J. Neurochem. 111 (4), 1022-1030 (2009)
Background Reference 02
Edwards, T.L., et.al., Biochem. J. 423 (1), 31-39 (2009) .
Other Product Names
Spartin, Spastic paraplegia 20 protein, Trans-activated by hepatitis C virus core protein 1, SPG20, KIAA0610, TAHCCP1
Tested Applications
WB, IHC-P, Flow
Protein ID
50401600
Physical Properties
Liquid
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
217871-HRP 100 µL
VEGFR2, Phosphorylated (Tyr1212) (Vascular Endothelial Growth Factor Receptor 2, VEGF Receptor 2, VEGFR 2, VEGFR-2, VEGFR, CD309 Antigen, Fetal Liver Kinase 1, FLK1, Kinase Insert Domain Receptor, KDR, KRD1, Ly73, Protein Tyrosine Kinase Receptor FLK1) (HRP) discontinued
Ask
View Details