JIP1 Antibody
Product Specifications
Background
JIP1 is a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8) . This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2.
NCBI Gene ID
9479
Swiss Prot
Q9UQF2
Accession Number
Q9UQF2
Host
Rabbit
Reactivity
Human
Immunogen
This JIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 470-498 amino acids from the C-terminal region of human JIP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-744
Calculated Molecular Weight
78 kDa
Fragment
Rabbit Ig
Symbol
MAPK8IP1
NCBI Official Name
C-Jun-amino-terminal kinase-interacting protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Mooser, V., et.al., Genomics 55 (2), 202-208 (1999)
Other Product Names
C-Jun-amino-terminal kinase-interacting protein 1, JIP-1, JNK-interacting protein 1, Islet-brain 1, IB-1, JNK MAP kinase scaffold protein 1, Mitogen-activated protein kinase 8-interacting protein 1, MAPK8IP1, IB1, JIP1, PRKM8IP
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
17433093
Physical Properties
Liquid
Curated Selection
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