EXOC5 Antibody
Product Specifications
Background
EXOC5 is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
NCBI Gene ID
10640
Swiss Prot
O00471
Accession Number
O00471
Host
Rabbit
Reactivity
Human
Immunogen
This EXOC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-66 amino acids from the C-terminal region of human EXOC5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-741
Calculated Molecular Weight
82 kDa
Fragment
Rabbit Ig
Symbol
EXOC5
NCBI Official Name
Exocyst complex component 5
NCBI Organism
Homo sapiens
Background Reference 01
Kee, Y., et.al., Proc. Natl. Acad. Sci. U.S.A. 94 (26), 14438-14443 (1997)
Background Reference 02
Hsu, S.C., et.al., Neuron 20 (6), 1111-1122 (1998)
Other Product Names
Exocyst complex component 5, Exocyst complex component Sec10, hSec10, EXOC5, SEC10, SEC10L1
Tested Applications
WB, IHC-P, Flow
Physical Properties
Liquid
Curated Selection
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