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ARG1 Antibody

Product Specifications

Background

Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia.

NCBI Gene ID

383

Swiss Prot

P05089

Accession Number

P05089

Host

Rabbit

Reactivity

Human

Immunogen

This ARG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-322 amino acids from the C-terminal region of human ARG1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

35 kDa

Fragment

Rabbit Ig

Symbol

ARG1

NCBI Official Name

Arginase-1

NCBI Organism

Homo sapiens

Background Reference 01

Haraguchi, Y., et.al., J. Clin. Invest. 86 (1), 347-350 (1990)

Other Product Names

Arginase-1, Liver-type arginase, Type I arginase, ARG1

Tested Applications

WB, IHC-P, Flow

Protein ID

12230985

Physical Properties

Liquid

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