ALDH18A1 Antibody
Product Specifications
Background
ALDH18A1 is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine.
NCBI Gene ID
5832
Swiss Prot
P54886
Accession Number
P54886
Host
Rabbit
Reactivity
Human
Immunogen
This ALDH18A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-205 amino acids from the Central region of human ALDH18A1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-710
Calculated Molecular Weight
87 kDa
Fragment
Rabbit Ig
Symbol
ALDH18A1
NCBI Official Name
Delta-1-pyrroline-5-carboxylate synthase
NCBI Organism
Homo sapiens
Background Reference 01
Hu, C.A., et.al., Amino Acids 35 (4), 665-672 (2008)
Background Reference 02
Bicknell, L.S., et.al., Eur. J. Hum. Genet. 16 (10), 1176-1186 (2008)
Other Product Names
Delta-1-pyrroline-5-carboxylate synthase, P5CS, Aldehyde dehydrogenase family 18 member A1, Glutamate 5-kinase, GK, Gamma-glutamyl kinase, Gamma-glutamyl phosphate reductase, GPR, Glutamate-5-semialdehyde dehydrogenase, Glutamyl-gamma-semialdehyde dehydrogenase, ALDH18A1, GSAS, P5CS, PYCS
Tested Applications
WB, IHC-P, Flow
Protein ID
6226882
Physical Properties
Liquid
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