DGCR8 Antibody
Product Specifications
Background
MicroRNAs (miRNA) are a recently discovered family of short non-protein-coding RNAs that negatively regulate gene expression. Recent studies of miRNAs highlight a requirement for cell viability. Post-transcriptional silencing of target genes by miRNAs occurs either by targeting specific cleavage of homologous mRNAs, or by targeting specific inhibition of protein synthesis.
NCBI Gene ID
54487
Swiss Prot
Q8WYQ5
Accession Number
Q8WYQ5
Host
Rabbit
Reactivity
Human
Immunogen
This DGCR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 439-466 amino acids from the Central region of human DGCR8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
86 kDa
Fragment
Rabbit Ig
Symbol
DGCR8
NCBI Official Name
Microprocessor complex subunit DGCR8
NCBI Organism
Homo sapiens
Background Reference 01
Clague, J., et.al., Mol. Carcinog. 49 (2), 183-189 (2010)
Background Reference 02
Shenoy, A. et.al., PLoS ONE (9), E6971 (2009)
Other Product Names
Microprocessor complex subunit DGCR8, DiGeorge syndrome critical region 8, DGCR8, C22orf12, DGCRK6
Tested Applications
WB, Flow
Protein ID
23813990
Physical Properties
Liquid
Curated Selection
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