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ADAMTS18 Antibody

Product Specifications

Background

ADAMTS18 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. This protein has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor.

NCBI Gene ID

170692

Swiss Prot

Q8TE60

Accession Number

Q8TE60

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This ADAMTS18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1066-1095 amino acids from the C-terminal region of human ADAMTS18.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

135 kDa

Fragment

Rabbit Ig

Symbol

ADAMTS18

NCBI Official Name

A disintegrin and metalloproteinase with thrombospondin motifs 18

NCBI Organism

Homo sapiens

Background Reference 01

Zeng, W., et.al., Biochim. Biophys. Acta 1760 (3), 517-524 (2006)

Background Reference 02

Jin, H., et.al., Oncogene 26 (53), 7490-7498 (2007)

Other Product Names

A disintegrin and metalloproteinase with thrombospondin motifs 18, ADAM-TS 18, ADAM-TS18, ADAMTS-18, 3424-, ADAMTS18, ADAMTS21

Tested Applications

WB, IHC-P, Flow

Protein ID

296439427

Physical Properties

Liquid

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