ADCY8 Antibody
Product Specifications
Background
ADCY8 is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase provided by RefSeq].
NCBI Gene ID
114
Swiss Prot
P40145
Accession Number
P40145
Host
Rabbit
Reactivity
Human
Immunogen
This ADCY8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 946-972 amino acids from the Central region of human ADCY8.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-675
Calculated Molecular Weight
140 kDa
Fragment
Rabbit Ig
Symbol
ADCY8
NCBI Official Name
Adenylate cyclase type 8
NCBI Organism
Homo sapiens
Background Reference 01
Martin, A.C., et.al., Mol. Pharmacol. 75 (4), 830-842 (2009)
Other Product Names
Adenylate cyclase type 8, ATP pyrophosphate-lyase 8, Adenylate cyclase type VIII, Adenylyl cyclase 8, AC8, Ca (2+) /calmodulin-activated adenylyl cyclase, ADCY8
Tested Applications
WB, IHC-P, Flow
Protein ID
729242
Physical Properties
Liquid
Curated Selection
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