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ADCY8 Antibody

Product Specifications

Background

ADCY8 is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase provided by RefSeq].

NCBI Gene ID

114

Swiss Prot

P40145

Accession Number

P40145

Host

Rabbit

Reactivity

Human

Immunogen

This ADCY8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 946-972 amino acids from the Central region of human ADCY8.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

140 kDa

Fragment

Rabbit Ig

Symbol

ADCY8

NCBI Official Name

Adenylate cyclase type 8

NCBI Organism

Homo sapiens

Background Reference 01

Martin, A.C., et.al., Mol. Pharmacol. 75 (4), 830-842 (2009)

Other Product Names

Adenylate cyclase type 8, ATP pyrophosphate-lyase 8, Adenylate cyclase type VIII, Adenylyl cyclase 8, AC8, Ca (2+) /calmodulin-activated adenylyl cyclase, ADCY8

Tested Applications

WB, IHC-P, Flow

Protein ID

729242

Physical Properties

Liquid

Frequently Asked Questions

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