PLCL1 Antibody

Product Specifications

Background

PLCL1 is an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and sphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor (By similarity) . Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as a nhibitor of PPP1C.

NCBI Gene ID

5334

Swiss Prot

Q15111

Accession Number

Q15111

Host

Rabbit

Reactivity

Human

Immunogen

This PLCL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 149-176 amino acids from the N-terminal region of human PLCL1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

123 kDa

Fragment

Rabbit Ig

Symbol

PLCL1

NCBI Official Name

Inactive phospholipase C-like protein 1

NCBI Organism

Homo sapiens

Background Reference 01

Liu, Y.Z., et.al., PLoS ONE (9), E3160 (2008)

Other Product Names

Inactive phospholipase C-like protein 1, PLC-L1, Phospholipase C-deleted in lung carcinoma, Phospholipase C-related but catalytically inactive protein, PRIP, PLCL1