ITGA1 Antibody
Product Specifications
Background
ITGA1 is the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding.
NCBI Gene ID
3672
Swiss Prot
P56199
Accession Number
P56199
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This ITGA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 727-755 amino acids from the Central region of human ITGA1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
131 kDa
Fragment
Rabbit Ig
Symbol
ITGA1
NCBI Official Name
Integrin alpha-1
NCBI Organism
Homo sapiens
Background Reference 01
Bank, I., et.al., J. Clin. Immunol. 11 (1), 29-38 (1991)
Other Product Names
Integrin alpha-1, CD49 antigen-like family member A, Laminin and collagen receptor, VLA-1, CD49a, ITGA1
Tested Applications
WB, IHC-P
Protein ID
124056463
Physical Properties
Liquid
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