XPA Antibody
Product Specifications
Background
XPA is involved in DNA excision repair. It initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. This protein is required for UV-induced CHK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.
NCBI Gene ID
7507
Swiss Prot
P23025
Accession Number
P23025
Host
Rabbit
Reactivity
Human
Immunogen
This XPA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-250 amino acids from the C-terminal region of human XPA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
31 kDa
Fragment
Rabbit Ig
Symbol
XPA
NCBI Official Name
DNA repair protein complementing XP-A cells
NCBI Organism
Homo sapiens
Background Reference 01
States J.C., et.al., Hum. Mutat. 12:103-113 (1998) .
Other Product Names
DNA repair protein complementing XP-A cells, Xeroderma pigmentosum group A-complementing protein, XPA, XPAC
Tested Applications
WB, IHC-P, Flow
Protein ID
139816
Physical Properties
Liquid
Curated Selection
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