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SOD1 Antibody

Product Specifications

Background

SOD1 binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein.

NCBI Gene ID

6647

Swiss Prot

P00441

Accession Number

P00441

Host

Rabbit

Reactivity

Human

Immunogen

This SOD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 55-84 amino acids from the Central region of human SOD1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

16 kDa

Fragment

Rabbit Ig

Symbol

SOD1

NCBI Official Name

Superoxide dismutase [Cu-Zn]

NCBI Organism

Homo sapiens

Background Reference 01

Crapo, J.D., et.al., Proc. Natl. Acad. Sci. U.S.A. 89 (21), 10405-10409 (1992)

Other Product Names

Superoxide dismutase [Cu-Zn], Superoxide dismutase 1, hSod1, SOD1

Tested Applications

WB, IHC-P, IF, Flow

Physical Properties

Liquid

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