DIO2 Antibody
Product Specifications
Background
DIO2 belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3) .
NCBI Gene ID
1734
Swiss Prot
Q92813
Accession Number
Q92813
Host
Rabbit
Reactivity
Human
Immunogen
This DIO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-191 amino acids from the Central region of human DIO2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Pig
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
31 kDa
Fragment
Rabbit Ig
Symbol
DIO2
NCBI Official Name
Type II iodothyronine deiodinase
NCBI Organism
Homo sapiens
Background Reference 01
He, B., et.al., Prog. Neuropsychopharmacol. Biol. Psychiatry 33 (6), 986-990 (2009)
Background Reference 02
Heemstra, K.A., et.al., J. Clin. Endocrinol. Metab. 94 (6), 2144-2150 (2009)
Other Product Names
Type II iodothyronine deiodinase, 5DII, DIOII, Type 2 DI, Type-II 5'-deiodinase, DIO2, ITDI2, TXDI2
Tested Applications
WB, IHC-P, Flow
Protein ID
172045839
Physical Properties
Liquid
Frequently Asked Questions
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