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CNTNAP2 Antibody

Product Specifications

Background

CNTNAP2 is a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C omain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons, and mediates interactions between neurons and glia during nervous system development and is also involved in localization of potassium channels within differentiating axons.

NCBI Gene ID

26047

Swiss Prot

Q9UHC6

Accession Number

Q9UHC6

Host

Rabbit

Reactivity

Human

Immunogen

This CNTNAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1079-1106 amino acids from the Central region of human CNTNAP2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

148 kDa

Fragment

Rabbit Ig

Symbol

CNTNAP2

NCBI Official Name

Contactin-associated protein-like 2

NCBI Organism

Homo sapiens

Background Reference 01

Denisenko-Nehrbass, N., et.al., Eur. J. Neurosci. 17 (2), 411-416 (2003)

Background Reference 02

Nakayama, M., et.al., Genome Res. 12 (11), 1773-1784 (2002)

Other Product Names

Contactin-associated protein-like 2, Cell recognition molecule Caspr2, CNTNAP2, CASPR2 {ECO:0000303|PubMed:10624965}, KIAA0868

Tested Applications

WB, IHC-P

Protein ID

17433089

Physical Properties

Liquid

Frequently Asked Questions

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