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VIME Antibody

Product Specifications

Background

VIME is a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. This protein is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL) -derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling.

NCBI Gene ID

7431

Swiss Prot

P08670

Accession Number

P08670

Host

Rabbit

Reactivity

Human

Immunogen

This Vimentin antibody is generated from rabbits immunized with Vimentin recombinant protein.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Cell Cycle, Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

54 kDa

Fragment

Rabbit Ig

Symbol

VIM

NCBI Official Name

Vimentin

NCBI Organism

Homo sapiens

Background Reference 01

Morishima, N., Genes Cells (7), 401-414 (1999)

Other Product Names

Vimentin, VIM

Tested Applications

WB, IHC-P, Flow

Protein ID

55977767

Physical Properties

Liquid

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