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DSC1 Antibody

Product Specifications

Background

DSC1 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined.

NCBI Gene ID

1823

Swiss Prot

Q08554

Accession Number

Q08554

Host

Rabbit

Reactivity

Human

Immunogen

This DSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 659-687 amino acids from the C-terminal region of human DSC1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

100 kDa

Fragment

Rabbit Ig

Symbol

DSC1

NCBI Official Name

Desmocollin-1

NCBI Organism

Homo sapiens

Background Reference 01

Toulza, E., et.al., Genome Biol. (6), R107 (2007)

Background Reference 02

Descargues, P., et.al., J. Invest. Dermatol. 126 (7), 1622-1632 (2006)

Other Product Names

Desmocollin-1, Cadherin family member 1, Desmosomal glycoprotein 2/3, DG2/DG3, DSC1, CDHF1

Tested Applications

WB, IHC-P, Flow

Protein ID

223590198

Physical Properties

Liquid

Frequently Asked Questions

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