DSC1 Antibody
Product Specifications
Background
DSC1 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined.
NCBI Gene ID
1823
Swiss Prot
Q08554
Accession Number
Q08554
Host
Rabbit
Reactivity
Human
Immunogen
This DSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 659-687 amino acids from the C-terminal region of human DSC1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-578
Calculated Molecular Weight
100 kDa
Fragment
Rabbit Ig
Symbol
DSC1
NCBI Official Name
Desmocollin-1
NCBI Organism
Homo sapiens
Background Reference 01
Toulza, E., et.al., Genome Biol. (6), R107 (2007)
Background Reference 02
Descargues, P., et.al., J. Invest. Dermatol. 126 (7), 1622-1632 (2006)
Other Product Names
Desmocollin-1, Cadherin family member 1, Desmosomal glycoprotein 2/3, DG2/DG3, DSC1, CDHF1
Tested Applications
WB, IHC-P, Flow
Protein ID
223590198
Physical Properties
Liquid
Curated Selection
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