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RAB7 Antibody

Product Specifications

Background

RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. RAB7 is a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori.

NCBI Gene ID

7879

Swiss Prot

P51149

Accession Number

P51149

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

This RAB7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-204 amino acids from the C-terminal region of human RAB7.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

23 kDa

Fragment

Rabbit Ig

Symbol

RAB7A

NCBI Official Name

Ras-related protein Rab-7a

NCBI Organism

Homo sapiens

Background Reference 01

Davies, J.P., et.al., Genomics 41 (1), 131-134 (1997)

Background Reference 02

Vitelli, R., et.al., Biochem. Biophys. Res. Commun. 229 (3), 887-890 (1996)

Other Product Names

Ras-related protein Rab-7a, RAB7A, RAB7

Tested Applications

WB, IHC-P, Flow

Protein ID

1709999

Physical Properties

Liquid

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