RAB7 Antibody
Product Specifications
Background
RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. RAB7 is a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori.
NCBI Gene ID
7879
Swiss Prot
P51149
Accession Number
P51149
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
This RAB7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-204 amino acids from the C-terminal region of human RAB7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
23 kDa
Fragment
Rabbit Ig
Symbol
RAB7A
NCBI Official Name
Ras-related protein Rab-7a
NCBI Organism
Homo sapiens
Background Reference 01
Davies, J.P., et.al., Genomics 41 (1), 131-134 (1997)
Background Reference 02
Vitelli, R., et.al., Biochem. Biophys. Res. Commun. 229 (3), 887-890 (1996)
Other Product Names
Ras-related protein Rab-7a, RAB7A, RAB7
Tested Applications
WB, IHC-P, Flow
Protein ID
1709999
Physical Properties
Liquid
Curated Selection
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