ESRRA Antibody
Product Specifications
Background
ESRRA is a nuclear receptor that is closely related to the estrogen receptor. This protein acts as a site-specific transcription regulator and has been also shown to interact with estrogen and the transcripton factor TFIIB by direct protein-protein contact. The binding and regulatory activities of this protein have been demonstrated in the regulation of a variety of genes including lactoferrin, osteopontin, medium-chain acyl coenzyme A dehydrogenase (MCAD) and thyroid hormone receptor genes.
NCBI Gene ID
2101
Swiss Prot
P11474
Accession Number
P11474
Host
Rabbit
Reactivity
Human
Immunogen
This ESRRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 131-159 amino acids from the Central region of human ESRRA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
46 kDa
Fragment
Rabbit Ig
Symbol
ESRRA
NCBI Official Name
Steroid hormone receptor ERR1
NCBI Organism
Homo sapiens
Background Reference 01
Yang, N., et.al., J. Biol. Chem. 271 (10), 5795-5804 (1996)
Background Reference 02
Wiley, S.R., et.al., Genes Dev. (11), 2206-2219 (1993)
Other Product Names
Steroid hormone receptor ERR1, Estrogen receptor-like 1, Estrogen-related receptor alpha, ERR-alpha, Nuclear receptor subfamily 3 group B member 1, ESRRA, ERR1, ESRL1, NR3B1
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
215274146
Physical Properties
Liquid
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