PTK2 Antibody
Product Specifications
Background
PTK2 is a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. This protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies.
NCBI Gene ID
5747
Swiss Prot
Q05397
Accession Number
Q05397
Host
Rabbit
Reactivity
Human
Immunogen
This PTK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 396-423 amino acids from the Central region of human PTK2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat, Chicken
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-548
Calculated Molecular Weight
119 kDa
Fragment
Rabbit Ig
Symbol
PTK2
NCBI Official Name
Focal adhesion kinase 1
NCBI Organism
Homo sapiens
Background Reference 01
Calalb, M.B., et.al., Mol. Cell. Biol. 15 (2), 954-963 (1995)
Background Reference 02
Polte, T.R. et.al., Proc. Natl. Acad. Sci. U.S.A. 92 (23), 10678-10682 (1995)
Background Reference 03
Gervais, F.G., et.al., J. Biol. Chem. 273 (27), 17102-17108 (1998)
Other Product Names
Focal adhesion kinase 1, FADK 1, Focal adhesion kinase-related nonkinase, FRNK, Protein phosphatase 1 regulatory subunit 71, PPP1R71, Protein-tyrosine kinase 2, p125FAK, pp125FAK, PTK2, FAK, FAK1
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
3183518
Physical Properties
Liquid
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