PPP2R2B Antibody

Product Specifications

Background

PPP2R2B belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This protein is a beta isoform of the regulatory subunit B55 subfamily.

NCBI Gene ID

5521

Swiss Prot

Q00005

Accession Number

Q00005

Host

Rabbit

Reactivity

Human

Immunogen

This PPP2R2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-130 amino acids from the Central region of human PPP2R2B.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Neuroscience, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse, Pig, Rabbit, Rat, Xenopus

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

52 kDa

Fragment

Rabbit Ig

Symbol

PPP2R2B

NCBI Official Name

Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

NCBI Organism

Homo sapiens

Background Reference 01

Rajkiewicz, M., et.al., Neurol. Neurochir. Pol. 42 (6), 497-504 (2008)

Background Reference 02

Ben-Israel, H., et.al., J. Virol. 82 (19), 9381-9388 (2008)

Background Reference 03

Strack, S., et.al., J. Comp. Neurol. 392 (4), 515-527 (1998)

Other Product Names

Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform, PP2A subunit B isoform B55-beta, PP2A subunit B isoform PR55-beta, PP2A subunit B isoform R2-beta, PP2A subunit B isoform beta, PPP2R2B