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ADH5 Antibody

Product Specifications

Background

ADH5 is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis.

NCBI Gene ID

128

Swiss Prot

P11766

Accession Number

P11766

Host

Rabbit

Reactivity

Human

Immunogen

This ADH5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-239 amino acids from the Central region of human ADH5.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Obesity, Signal Transduction

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Rb

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

40 kDa

Fragment

Rabbit Ig

Symbol

ADH5

NCBI Official Name

Alcohol dehydrogenase class-3

NCBI Organism

Homo sapiens

Background Reference 01

Martins-de-Souza, D., et.al., Eur Arch Psychiatry Clin Neurosci 259 (3), 151-163 (2009)

Background Reference 02

Iborra, F.J., et.al., J. Histochem. Cytochem. 40 (12), 1865-1878 (1992)

Other Product Names

HGNC:253

Tested Applications

WB, IHC-P, Flow

Protein ID

113408

Physical Properties

Liquid

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