ADH5 Antibody
Product Specifications
Background
ADH5 is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis.
NCBI Gene ID
128
Swiss Prot
P11766
Accession Number
P11766
Host
Rabbit
Reactivity
Human
Immunogen
This ADH5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-239 amino acids from the Central region of human ADH5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rb
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
40 kDa
Fragment
Rabbit Ig
Symbol
ADH5
NCBI Official Name
Alcohol dehydrogenase class-3
NCBI Organism
Homo sapiens
Background Reference 01
Martins-de-Souza, D., et.al., Eur Arch Psychiatry Clin Neurosci 259 (3), 151-163 (2009)
Background Reference 02
Iborra, F.J., et.al., J. Histochem. Cytochem. 40 (12), 1865-1878 (1992)
Other Product Names
HGNC:253
Tested Applications
WB, IHC-P, Flow
Protein ID
113408
Physical Properties
Liquid
Curated Selection
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