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GSDMB Antibody

Product Specifications

Background

GSDMB is a protein with 3' exonuclease activity. Enzymes with this activity are involved in DNA replication, repair, and recombination. Similarity to an E. coli protein suggests that this enzyme may be a subunit of DNA polymerase III, which does not have intrinsic exonuclease activity.

NCBI Gene ID

55876

Swiss Prot

Q8TAX9

Accession Number

Q8TAX9

Host

Rabbit

Reactivity

Human

Immunogen

This GSDMB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-237 amino acids from the Central region of human GSDMB.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

47 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GSDMB

NCBI Official Name

Gasdermin-B

NCBI Organism

Homo sapiens

Background Reference 01

Hur, J.W., et.al., Rheumatol. Int. 28 (8), 783-789 (2008)

Background Reference 02

Chen, M.J., et.al., Nucleic Acids Res. 35 (8), 2682-2694 (2007)

Other Product Names

Gasdermin-B, Gasdermin-like protein, GSDMB, GSDML

Tested Applications

WB

Protein ID

182647404

Physical Properties

Liquid

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