GSDMB Antibody
Product Specifications
Background
GSDMB is a protein with 3' exonuclease activity. Enzymes with this activity are involved in DNA replication, repair, and recombination. Similarity to an E. coli protein suggests that this enzyme may be a subunit of DNA polymerase III, which does not have intrinsic exonuclease activity.
NCBI Gene ID
55876
Swiss Prot
Q8TAX9
Accession Number
Q8TAX9
Host
Rabbit
Reactivity
Human
Immunogen
This GSDMB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-237 amino acids from the Central region of human GSDMB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
47 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
GSDMB
NCBI Official Name
Gasdermin-B
NCBI Organism
Homo sapiens
Background Reference 01
Hur, J.W., et.al., Rheumatol. Int. 28 (8), 783-789 (2008)
Background Reference 02
Chen, M.J., et.al., Nucleic Acids Res. 35 (8), 2682-2694 (2007)
Other Product Names
Gasdermin-B, Gasdermin-like protein, GSDMB, GSDML
Tested Applications
WB
Protein ID
182647404
Physical Properties
Liquid
Curated Selection
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