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PIGR Antibody

Product Specifications

Background

PIGR binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.

NCBI Gene ID

5284

Swiss Prot

P01833

Accession Number

P01833

Host

Rabbit

Reactivity

Human

Immunogen

This PIGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 646-672 amino acids from the C-terminal region of human PIGR.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

83 kDa

Fragment

Rabbit Ig

Symbol

PIGR

NCBI Official Name

Polymeric immunoglobulin receptor

NCBI Organism

Homo sapiens

Background Reference 01

Ewing, R.M., et.al., Mol. Syst. Biol. 3, 89 (2007)

Background Reference 02

Orzech, E., Cohen, S., et.al., J. Biol. Chem. 275 (20), 15207-15219 (2000)

Other Product Names

Polymeric immunoglobulin receptor, PIgR, Poly-Ig receptor, Hepatocellular carcinoma-associated protein TB6, Secretory component, PIGR

Tested Applications

WB, IHC-P, IF, Flow

Protein ID

150421625

Physical Properties

Liquid

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