PIGR Antibody
Product Specifications
Background
PIGR binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
NCBI Gene ID
5284
Swiss Prot
P01833
Accession Number
P01833
Host
Rabbit
Reactivity
Human
Immunogen
This PIGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 646-672 amino acids from the C-terminal region of human PIGR.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
83 kDa
Fragment
Rabbit Ig
Symbol
PIGR
NCBI Official Name
Polymeric immunoglobulin receptor
NCBI Organism
Homo sapiens
Background Reference 01
Ewing, R.M., et.al., Mol. Syst. Biol. 3, 89 (2007)
Background Reference 02
Orzech, E., Cohen, S., et.al., J. Biol. Chem. 275 (20), 15207-15219 (2000)
Other Product Names
Polymeric immunoglobulin receptor, PIgR, Poly-Ig receptor, Hepatocellular carcinoma-associated protein TB6, Secretory component, PIGR
Tested Applications
WB, IHC-P, IF, Flow
Protein ID
150421625
Physical Properties
Liquid
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