LTA Antibody
Product Specifications
Background
LTA, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis.
NCBI Gene ID
4049
Swiss Prot
P01374
Accession Number
P01374
Host
Rabbit
Reactivity
Human
Immunogen
This LTA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-72 amino acids from the Central region of human LTA.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Immunology, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
22 kDa
Fragment
Rabbit Ig
Symbol
LTA
NCBI Official Name
Lymphotoxin-alpha
NCBI Organism
Homo sapiens
Background Reference 01
Buonaguro, L., et.al., J. Virol. 66 (12), 7159-7167 (1992)
Background Reference 02
Fukushima, K., et.al., Arch. Biochem. Biophys. 304 (1), 144-153 (1993)
Other Product Names
Lymphotoxin-alpha, LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA, TNFB, TNFSF1
Tested Applications
WB, IHC-P, Flow
Protein ID
135940
Physical Properties
Liquid
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