Calcineurin Antibody
Product Specifications
Background
PPP3CA is a calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. PPP3CA dephosphorylates HSPB1 and SSH1.
NCBI Gene ID
5530
Swiss Prot
Q08209
Accession Number
Q08209
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This Calcineurin (PPP3CA) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-51 amino acids from the N-terminal region of human Calcineurin (PPP3CA) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Immunology, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-485
Calculated Molecular Weight
59 kDa
Fragment
Rabbit Ig
Symbol
PPP3CA
NCBI Official Name
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
NCBI Organism
Homo sapiens
Background Reference 01
Rodriguez, A., et al., J. Biol. Chem. 280 (11) :9980-9984 (2005) . Shirane, M., et al., Nat. Cell Biol. 5 (1) :28-37 (2003) . Bengoechea-Alonso, M.T., et al., Nitric Oxide 8 (1) :65-74 (2003) . Huai, Q., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (19) :12037-12042 (2002) . Bennasser, Y., et al., Virology 303 (1) :174-180 (2002) .
Other Product Names
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, CAM-PRP catalytic subunit, Calmodulin-dependent calcineurin A subunit alpha isoform, PPP3CA, CALNA, CNA
Tested Applications
WB, IHC-P
Protein ID
1352673
Physical Properties
Liquid
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