Calcineurin Antibody

Product Specifications

Background

PPP3CA is a calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. PPP3CA dephosphorylates HSPB1 and SSH1.

NCBI Gene ID

5530

Swiss Prot

Q08209

Accession Number

Q08209

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

This Calcineurin (PPP3CA) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 21-51 amino acids from the N-terminal region of human Calcineurin (PPP3CA) .

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Immunology, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Bovine, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

59 kDa

Fragment

Rabbit Ig

Symbol

PPP3CA

NCBI Official Name

Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform

NCBI Organism

Homo sapiens

Background Reference 01

Rodriguez, A., et al., J. Biol. Chem. 280 (11) :9980-9984 (2005) . Shirane, M., et al., Nat. Cell Biol. 5 (1) :28-37 (2003) . Bengoechea-Alonso, M.T., et al., Nitric Oxide 8 (1) :65-74 (2003) . Huai, Q., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (19) :12037-12042 (2002) . Bennasser, Y., et al., Virology 303 (1) :174-180 (2002) .

Other Product Names

Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, CAM-PRP catalytic subunit, Calmodulin-dependent calcineurin A subunit alpha isoform, PPP3CA, CALNA, CNA