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MEG2 Antibody

Product Specifications

Background

MEG2 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis.

NCBI Gene ID

5780

Swiss Prot

P43378

Accession Number

P43378

Host

Rabbit

Reactivity

Human

Immunogen

This MEG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 477-505 amino acids from the C-terminal region of human MEG2.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

68 kDa

Fragment

Rabbit Ig

Symbol

PTPN9

NCBI Official Name

Tyrosine-protein phosphatase non-receptor type 9

NCBI Organism

Homo sapiens

Background Reference 01

Kruger, J.M., et al., J. Biol. Chem. 277 (4) :2620-2628 (2002) .

Background Reference 02

Qi, Y., et al., J. Cell. Biochem. 86 (1) :79-89 (2002) .

Background Reference 03

Gu, M., et al., Proc. Natl. Acad. Sci. U.S.A. 89 (7) :2980-2984 (1992) .

Other Product Names

Tyrosine-protein phosphatase non-receptor type 9, Protein-tyrosine phosphatase MEG2, PTPase MEG2, PTPN9

Tested Applications

WB, IHC-P

Protein ID

1172724

Physical Properties

Liquid

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