Guanylyl Cyclase beta 1 Antibody

Product Specifications

Background

Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha and a beta subunit, catalyzes the conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide and nitrovasodilator drugs.

NCBI Gene ID

2983

Swiss Prot

Q02153

Accession Number

Q02153

Host

Rabbit

Reactivity

Human

Immunogen

This GUCY1B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected between 589-619 amino acids of human GUCY1B3.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

71 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

GUCY1B3

NCBI Official Name

Guanylate cyclase soluble subunit beta-1

NCBI Organism

Homo sapiens

Background Reference 01

Russwurm, M., et al., J. Biol. Chem. 276 (48) :44647-44652 (2001) .

Background Reference 02

Lucas, K.A., et al., Pharmacol. Rev. 52 (3) :375-414 (2000) .

Background Reference 03

Papapetropoulos, A., et al., J. Cell. Physiol. 167 (2) :213-221 (1996) .

Background Reference 04

Giuili, G., et al., Hum. Genet. 91 (3) :257-260 (1993) .

Other Product Names

Guanylate cyclase soluble subunit beta-1, GCS-beta-1, Guanylate cyclase soluble subunit beta-3, GCS-beta-3, Soluble guanylate cyclase small subunit, GUCY1B3, GUC1B3, GUCSB3, GUCY1B1