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MVP Antibody

Product Specifications

Background

MVK encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of MVK results in mevalonic aciduria.

NCBI Gene ID

4598

Swiss Prot

Q03426

Accession Number

Q03426

Host

Rabbit

Reactivity

Human

Immunogen

This MVK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-47 amino acids from the N-terminal region of human MVK.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cancer, Obesity, Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=63-443

Calculated Molecular Weight

42 kDa

Fragment

Rabbit Ig

Applications Notes

For WB starting dilution is: 1:1000

Symbol

MVK

NCBI Official Name

Mevalonate kinase

NCBI Organism

Homo sapiens

Background Reference 01

Stojanov, S., et al., Arthritis Rheum. 50 (6) :1951-1958 (2004) .

Background Reference 02

Nair, A.K., et al., J. Biol. Chem. 279 (15) :14937-14944 (2004) .

Background Reference 03

Simon, A., et al., Neurology 62 (6) :994-997 (2004) .

Background Reference 04

Houten, S.M., et al., J. Biol. Chem. 278 (8) :5736-5743 (2003) .

Other Product Names

Mevalonate kinase, MK, MVK

Tested Applications

WB

Protein ID

417215

Physical Properties

Liquid

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