MVP Antibody
Product Specifications
Background
MVK encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of MVK results in mevalonic aciduria.
NCBI Gene ID
4598
Swiss Prot
Q03426
Accession Number
Q03426
Host
Rabbit
Reactivity
Human
Immunogen
This MVK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-47 amino acids from the N-terminal region of human MVK.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
42 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MVK
NCBI Official Name
Mevalonate kinase
NCBI Organism
Homo sapiens
Background Reference 01
Stojanov, S., et al., Arthritis Rheum. 50 (6) :1951-1958 (2004) .
Background Reference 02
Nair, A.K., et al., J. Biol. Chem. 279 (15) :14937-14944 (2004) .
Background Reference 03
Simon, A., et al., Neurology 62 (6) :994-997 (2004) .
Background Reference 04
Houten, S.M., et al., J. Biol. Chem. 278 (8) :5736-5743 (2003) .
Other Product Names
Mevalonate kinase, MK, MVK
Tested Applications
WB
Protein ID
417215
Physical Properties
Liquid
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