ITPKB Antibody

Product Specifications

Background

ITPKB regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins (1,3,4,5) P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.

NCBI Gene ID

3707

Swiss Prot

P27987

Accession Number

P27987

Host

Rabbit

Reactivity

Human

Immunogen

This ITPKB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-54 amino acids from the N-terminal region of human ITPKB.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Signal Transduction

Purification

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

Concentration

Batch dependent

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Calculated Molecular Weight

102 kDa

Fragment

Rabbit Ig

Symbol

ITPKB

NCBI Official Name

Inositol-trisphosphate 3-kinase B

NCBI Organism

Homo sapiens

Background Reference 01

Dewaste, V., et al., Biochem. Biophys. Res. Commun. 291 (2) :400-405 (2002) .

Background Reference 02

Woodring, P.J., et al., J. Biol. Chem. 272 (48) :30447-30454 (1997) .

Background Reference 03

Erneux, C., et al., Genomics 14 (2) :546-547 (1992) .

Background Reference 04

Takazawa, K., et al., Biochem. J. 272 (1) :107-112 (1990) .

Other Product Names

Inositol-trisphosphate 3-kinase B, Inositol 1,5-trisphosphate 3-kinase B, IP3 3-kinase B, IP3K B, InsP 3-kinase B, ITPKB

Tested Applications

WB, IHC-P, Flow

Protein ID

62906885

Physical Properties

Liquid

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