DGKB Antibody
Product Specifications
Background
Diacylglycerol (DAG) is an allosteric activator of protein kinase C. DAG also participates in regulating RAS and RHO family proteins by activating the guanine nucleotide exchange factors VAV and RASGRP1. DAG is also involved in the synthesis of phospholipids and triacylglycerols. Tight regulation of DAG levels is achieved via DAG kinases (DGKs), which remove DAG by phosphorylate it to phosphatidic acid. Several mammalian isozymes of DAGK have been identified
NCBI Gene ID
1607
Swiss Prot
Q9Y6T7
Accession Number
Q9Y6T7
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This DGKB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 773-804 amino acids from the C-terminal region of human DGKB.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Product Datasheet
https://www.prosci-inc.com/?datasheet_sku=63-408
Calculated Molecular Weight
91 kDa
Fragment
Rabbit Ig
Symbol
DGKB
NCBI Official Name
Diacylglycerol kinase beta
NCBI Organism
Homo sapiens
Background Reference 01
Caricasole, A., et al., J. Biol. Chem. 277 (7) :4790-4796 (2002) .
Other Product Names
Diacylglycerol kinase beta, DAG kinase beta, 90 kDa diacylglycerol kinase, Diglyceride kinase beta, DGK-beta, DGKB, DAGK2, KIAA0718
Tested Applications
WB, IHC-P
Protein ID
12643960
Physical Properties
Liquid
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