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WEE1 Antibody

Product Specifications

Background

WEE1 is a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

NCBI Gene ID

7465

Swiss Prot

P30291

Accession Number

P30291

Host

Rabbit

Reactivity

Human

Immunogen

This WEE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 604-634 amino acids from the C-terminal region of human WEE1.

Clonality

Polyclonal

Conjugation

Unconjugated

Type

Primary Antibodies

Field of Research

Cell Cycle

Purification

This antibody is purified through a protein A column, followed by peptide affinity purification.

Concentration

Batch dependent

Homology

Predicted species reactivity based on immunogen sequence: Mouse, Rat

Buffer

Supplied in PBS with 0.09% (W/V) sodium azide.

Modification

None

Shipping Conditions

Blue Ice

Storage Conditions

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Product Datasheet

https://www.prosci-inc.com/?datasheet_sku=63-399

Calculated Molecular Weight

72 kDa

Fragment

Rabbit Ig

Symbol

WEE1

NCBI Official Name

Wee1-like protein kinase

NCBI Organism

Homo sapiens

Background Reference 01

Kawasaki, H., et al., Oncogene 22 (44) :6839-6844 (2003) .

Background Reference 02

Hashimoto, O., et al., Mol. Carcinog. 36 (4) :171-182 (2003) .

Background Reference 03

Yuan, H., et al., J. Virol. 77 (3) :2063-2070 (2003) .

Background Reference 04

Masaki, T., et al., Hepatology 37 (3) :534-543 (2003) .

Other Product Names

Wee1-like protein kinase, WEE1hu, Wee1A kinase, WEE1

Tested Applications

WB, IHC-P

Protein ID

1351419

Physical Properties

Liquid

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