WEE1 Antibody
Product Specifications
Background
WEE1 is a nuclear protein, which is a tyrosine kinase belonging to the Ser/Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2/cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.
NCBI Gene ID
7465
Swiss Prot
P30291
Accession Number
P30291
Host
Rabbit
Reactivity
Human
Immunogen
This WEE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 604-634 amino acids from the C-terminal region of human WEE1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
72 kDa
Fragment
Rabbit Ig
Symbol
WEE1
NCBI Official Name
Wee1-like protein kinase
NCBI Organism
Homo sapiens
Background Reference 01
Kawasaki, H., et al., Oncogene 22 (44) :6839-6844 (2003) .
Background Reference 02
Hashimoto, O., et al., Mol. Carcinog. 36 (4) :171-182 (2003) .
Background Reference 03
Yuan, H., et al., J. Virol. 77 (3) :2063-2070 (2003) .
Background Reference 04
Masaki, T., et al., Hepatology 37 (3) :534-543 (2003) .
Other Product Names
Wee1-like protein kinase, WEE1hu, Wee1A kinase, WEE1
Tested Applications
WB, IHC-P
Protein ID
1351419
Physical Properties
Liquid
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