PBP Antibody

PBP binds ATP, opioids and phosphatidylethanolamine, exhibiting a lower affinity for phosphatidylinositol and phosphatidylcholine. This serine protease inhibitor inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase. PBP contains hippocampal cholinergic neurostimulating peptide (HCNP), which may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase.

This PBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 137-167 amino acids from the Central region of human PBP.

Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Tohdoh, N., et al., Brain Res. Mol. Brain Res. 30 (2) :381-384 (1995) . Hori, N., et al., Gene 140 (2) :293-294 (1994) . Seddiqi, N., et al., J. Mol. Evol. 39 (6) :655-660 (1994) . Moore, C., et al., Brain Res. Mol. Brain Res. 37 (1-2), 74-78 (1996) .

Phosphatidylethanolamine-binding protein 1, PEBP-1, HCNPpp, Neuropolypeptide h3, Prostatic-binding protein, Raf kinase inhibitor protein, RKIP, Hippocampal cholinergic neurostimulating peptide, HCNP, PEBP1, PBP, PEBP